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Genomics and Immunotherapy: Yielding Advances in Cancer Care

KEY POINT

Recently published articles reflect the rich tapestry of advances in gene-expression profiling as a means of identifying prognostic subclasses among patients with acute myeloid leukemia and for immunotherapy of various cancer types.

SOURCES

Bullinger L et al. Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. N Engl J Med. 2004;350:1605–16.

Valk PJM et al. Prognostically useful gene-expression profiles in acute myeloid leukemia. N Engl J Med. 2004;350:1617–28.

Grimwade D, Haferlach T. Gene-expression profiling in acute myeloid leukemia [editorial]. N Engl J Med. 2004;350:1676–8.

Liu E, Karuturi KR. Microarrays and clinical investigations. N Engl J Med. 2004;350:1595–7.

Rosenberg SA. Shedding light on immunotherapy for cancer. N Engl J Med. 2004;350:1461–2.