Oncology

Back to articles

Bisphosphonates Proving Beneficial in Women with Breast Cancer

KEY POINT

Bisphosphonates can prevent the osteoporosis that can develop in women being treated for breast cancer with bone-depleting hormonal agents. Researchers are also finding that the drugs can help prevent bone metastases and lengthen survival if breast cancer does spread to bone.

SOURCES

Gnant M et al. Zoledronic acid effectively counteracts cancer treatment induced bone loss (CTIBL) in premenopausal breast cancer patients receiving adjuvant endocrine treatment with goserelin plus anastrozole versus goserelin plus tamoxifen—bone density subprotocol results of a randomized multicenter trial (ABCSG-12). Paper presented at the 27th annual San Antonio Breast Cancer Symposium, December 8–11, 2004.

Powles T et al. Oral clodronate (Bonefos) reduces skeletal complications and mortality in breast cancer patients with bone metastases: retrospective analysis of patients from a randomized, placebo-controlled trial. Paper presented at the 27th annual San Antonio Breast Cancer Symposium, December 8–11, 2004.