Oncology

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Biologic Therapies: Best Hope for Advanced Lung Cancers?

KEY POINT

Two new studies of small-cell and non–small-cell lung cancers reflect the sometimes real but quite limited progress medical researchers are making in increasing the effectiveness of chemotherapy. Because chemotherapy is “nonspecific, nonselective, and toxic,” an editorialist commenting on the studies recommended that new studies of these conditions be aimed at prevention, early detection, and use of specific biologic agents.

SOURCES

Noda K et al. Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer. N Engl J Med. 2002;346:85–91.

Schiller JH et al. Comparison of four chemotherapy regimens for advanced non–small-cell lung cancer. N Engl J Med. 2002;346:92–8.

Carney DN. Lung cancer—time to move on from chemotherapy [editorial]. N Engl J Med. 2002;346:126–7.