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Unintended benefits: Can antihypertensives directly prevent Alzheimer dementia?

KEY POINT

Two recent studies demonstrated protective effects of antihypertensive agents against cognitive decline in older adults. In the first study, Japanese-American men over age 75 who were taking beta-blockers had a lower risk of cognitive impairment than those taking no antihypertensive agent. The second study demonstrated protective effects of diuretics, angiotensin receptor blockers, ACE inhibitors, and beta blockers against Alzheimer disease dementia in individuals over age 75 years.