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High-dose influenza vaccine more effective than standard dose for nursing home residents

September 18, 2017
  • Advising on this article:
  • John D. Grabenstein

KEY POINT

Older people residing in nursing homes who received the high-dose influenza vaccine (Fluzone High-Dose—Sanofi Pasteur) had a lower risk of respiratory-related hospital admissions, pneumonia hospitalizations, and all-cause hospitalizations compared with those who were given the standard-dose influenza vaccine, according to results of a large trial published in Lancet Respiratory Medicine.

SOURCES

Gravenstein S, et al. Comparative effectiveness of high-dose versus standard-dose influenza vaccination on numbers of US nursing home residents admitted to hospital: A cluster-randomised trial. Lancet Respir Med. 2017;[Epub ahead of print].

Widdowson MA, et al. High-dose influenza vaccine in nursing home residents: Not to be sneezed at. Lancet Respir Med. 2017;[Epub ahead of print]. 

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