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Vitamin K antagonists’ risks and benefits in the oldest patients

KEY POINT

Use of vitamin K antagonists in patients aged 90 years or older was associated with a slight increase in the risk of bleeding compared with patients in their 70s. The risk of thrombosis was higher in patients in their 90s and 80s compared with those in their 70s, according to results of a matched cohort study published online in JAMA Internal Medicine.

SOURCES

Kooistra, HA et al. Risk of bleeding and thrombosis in patients 70 years or older using vitamin K antagonists. JAMA Intern Med. 2016;[Epub ahead of print].

Parks AL, et al. Anticoagulation in the very old. JAMA Intern Med. 2016;[Epub ahead of print].