Drug Interactions Corner

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Drug interaction alerts and override reasons can be substantially improved


An assessment of drug–drug interaction (DDI) alert override reasons in electronic health records (EHRs) found that override reasons were variable, with many not actionable and some irrelevant to the DDI. The report, published in the Journal of the American Medical Informatics Association, suggests that both the quality of alerts and alert override reasons need substantial improvement and should be more specific to the interaction and the patient.


Wright A, et al. Structured override reasons for drug–drug interaction alerts in electronic health records. J Am Med Inform Assoc. 2019;[Epub ahead of print].